miRNA service
AcceGen Biotech offers high quality service for construction of miRNA sponge vector clones to assist researchers worldwide on their miRNA studies. MicroRNAs (miRNAs) are short non-coding RNA molecules that regulate the expression of their target genes at the post-transcriptional level by binding to their respective mRNAs. Upon hybridisation of the miRNA/messenger (m)RNA duplex, the target mRNA is cleaved and degraded or blocked from translation. The miRNAs represent key players in the regulation of multiple genes, and thus, virtually all cell processes, including cell cycle regulation, apoptosis, differentiation, and metabolism.